I hope it's the same for you! His Drs says theres no standard line second-line treatment . It is important to get any infection treated as soon as possible. If you get a high temperature, let your health care teamknow straight away. Nausea is rotten . Use a good, rich thick lotion. One former member used to drink cold water while being infused with the oxy and it prevented a lot of the cold issues. I know I won't put gloves on to get things out of the fridge, so I pull my sleeves down over my hands. Patients were randomly assigned (1:1) to chemotherapy every 3 weeks (intravenous oxaliplatin 130 mg/m 2 on day 1 plus either oral S-1 40 mg/m 2 [SOX] or oral capecitabine 1000 mg/m 2 [CAPOX], twice daily on days 1-14), in addition to either 360 mg nivolumab intravenously every 3 weeks (nivolumab plus chemotherapy group) or placebo (placebo plus chemotherapy group). But it has subsided. So I had ginger snaps guilt free. Our Cancer Information Nurse Specialists are dedicated cancer nurses available to talk to on our Macmillan Cancer Support Line. The capecitabine doesn't seem too bad. Your nurse can give you more advice. Stage 4 means that the cancer has spread to one or more other organs. The main problems I've had was the Peripheral Neuropathy which started near the end of my treatment. Your doctor will tell you the amount (dose) of capecitabine you need to take. If you have sex during a course of this treatment, you should use barrier protection such as a condom or dental dam. Isle of Man company number 4694F. As the others stated, getting out of bed and doing, certainly helps you past the mental/emotional aspects of doing chemo. The difference in my mum was amazing and just gave her some quality of life again . They may give you a copy of the treatment plan to take home with you. Your doctor will advise you not to get pregnant or make someone pregnant while having this treatment. Patients in both groups received adjuvant chemotherapy (capecitabine or fluorouracil and oxaliplatin) after CRT. Always tell your dentist you are having cancer treatment. I was warned not to eat or drink, anything cold as it could swelling. oxaliplatin and capecitabine (CAPOX) before CRT and TME in pa-tients with poor prognosis rectal cancer in a single-arm phase II trial (EXPERT).30 Patients received four cycles of CAPOX followed by capecitabine CRT, TME, and 12 weeks of adjuvant capecitabine. Randomisation was done . Tell your nurse or doctor immediatelyif at any time you feel unwell. The oxilaplatin causes neuropathy and cold sensitivity. Most people get it along with Xeloda. Lippincott, Williams and Wilkins, 2012. Drink plenty of fluids and eat as much fresh fruit and vegetables as you can. You may have tests to see how well your heart is working. 1-21 Capecitabine 2625mg/m BD PO All patients must have documented DPYD status and capecitabine doses adjusted accordingly prior to commencing treatment as per local practice. Your doctor or nurse can give you more information. 2. If you have any of these symptoms, you should stop taking the capecitabine tablets until you have spoken to your doctor. Registered office: 89 Albert Embankment, London SE1 7UQ. How often and how severe the side effects are can vary from person to person. Tell your doctor if you have these symptoms. Your nurse will give you advice about managing your side effects. God bless us all troopers!! It is normal. Contact a doctor straight away if you have any of the following symptoms: Read more about treatment for bowel cancer, Find out more about having a DPD deficiency, drop in thenumber ofplatelets in your blood, skin on your hands and feet may become sore, red, or may peel, Read more about how to cope with side effects, Find out more about the COVID-19 vaccine and cancer. The drugs may harm a developing baby. Oh well! Accessing the HOPE course through Macmillan Wellsprings story. Try different foods to find out what tastes best to you. Your nurse will tell you when your treatment is likely to be ready. I had a touch of each possible side effect, but limited. Your oncologist or the financial counsel at your CA center should have info on these. You usually take the tablets twice a day, about 12 hours apart. The only thing I can think of is to get a pair of gloves that you can use easily that will insulate against the cold. FOLFIRI Protocol V1.1. This is to make sure they work as well as possible for you. Hi, been a few years since I've been on here, I had bowel cancer in Aug 2009, since then I've had secondary cancer in various places, at the moment I'm stage 4 and have small tumours in my throat,lung and left shoulder, told it's slow growing, this is the second time I've hadOxaliplatin but having capecitabine tablets for 2 weeks as well, I'm on my 2nd session of 4 and am having constanttinnitus, has anyone else suffered with this as I'm thinking of cutting out the Oxaliplatin for the last 2 sessions to save my hearing or am I being over causious, many thanks. You may also get mouth ulcers. 1,2. I told the doctor at my next review before my second treatment and in my case because the pains were so bad they did reduce the strength of the treatment. This treatment may cause you discomfort when you pass urine (pee). Doctors usually recommend that people with cancer have a flu vaccination and a coronavirus (covid) vaccination. For further information about this treatment go to the electronic Medicines Compendium (eMC)website. Xeloda is the pill form of 5-FU and you take the pills twice a day for a week. This is called hand-foot syndrome or palmar plantar syndrome. Ask your doctor or pharmacisthow long you should avoid live vaccinations. We help people get through cancer. You can talk to your cancer doctor about your risk of having DPD deficiency before you start treatment. It is also known as colorectal cancer. If rectal cancer comes back (recurs), it usually comes back in a distant site such as the . Since I am so skinny it seems like it's a tendon protruding on my skin. The second week I was eating normally. They can slow down your drip if this happens. If your immune system is weak, you need to avoid live vaccinations. Before starting treatment with capecitabine you have a blood test to check levels of an enzyme called dihydropyrimidine dehydrogenase (DPD). XELOX and CAPOX are different names for the same combination of chemotherapy drugs. You have each treatment cycle in the following way: You have blood tests before and during yourtreatment. My dose is three tablets twice a . I had to quit my job due to my chemo therapy. Introduction & Objective: The combination of oxaliplatin and capecitabine has demonstrated its effect against various gastrointestinal cancers. Always take your tablets exactly as explained. Traci. Tell your treatment teamif you have this. This treatment can cause your blood sugar and sodium levels to go up. They include: Numbness or tingling in fingers or toesis often temporary and can improve after youfinish treatment. I second what everyone said about keeping your hands and feet warm while on the oxaliplatin. I did not have a port and after a few treatments, my infusion arm would feel sort of numb and tingly - went away in a week or two and was totally tolerable. This usually goes back to normal when your treatment finishes. Aims: To determine the efficacy of the combination of oxaliplatin and capecitabine in patients with advanced colorectal cancer. I only took off infusion day and worked and worked out the rest of the time. That's a very annoying side effect. If you have pain or notice any change in your vision, always tell your doctor or nurse. This treatment may affect the nerves, which can cause numb, tingling or painful hands or feet. This treatment may also cause blurry vision. Capecitabine plus oxaliplatin compared with fluorouracil and folinic acid as adjuvant therapy for stage III colon cancer. You may get a bitter or metal taste in your mouth. Help to Overcome Problems Effectively. FOLFIRNOX can be used in different ways. Let your healthcare team know straight away if you have any bleeding. Sickness, taste changes or tiredness can put you off food and drinks. The lab work showed I had Stage 3 cancer with 3 of 27 lymph nodes affected. Some people may have side effects while they are being given the chemotherapy or shortly after they have it: Some people have an allergic reaction while having this treatment. They also check how well your liver and kidneys are working. In addition, oxaliplatin in combination with 5-FU The tube stays in place throughout the course of treatment. Kick it to the side and be positve. Capecitabine may cause severediarrhoea. At the end of the rest period, you start your second cycle of XELOX. Keep them in the original package and at room temperature, away from heat and direct sunlight. Rarely, these may be life-threatening. I guess that makes me T3 N1b M0. You may have: Tell your doctor if you have any unexplained bruising or bleeding. These are both inactivated vaccinations that can help reduce the risk of infection. Repeat every 21 days for 8 cycles for high-risk stage III colon cancer (any T4 and . This is who we mean when we mention doctor, nurse or pharmacist in this information. Things like door knobs and not only things in the fridge but the fridge handle just to get into it. Always tell other doctors, nurses, pharmacists or dentists that youre having this treatment. Wear gloves and I even wore flip flops in the shower to keep my feet warm. Less commonly you might also bleed from other areas of the body for other reasons. If cisplatin is substituted by oxaliplatin and 5-FU by . Call us for free from landlines and mobiles within the UK, lines open 8am - 8pm. Were here to provide physical, financial and emotional support. I was never on the Xeloda so can't help there, but hope your treatment goes well with minimal side effects. The length of time depends on the treatment you are having. All three drugs, whether used singly or as part of a combination regimen, are relatively well tolerated and have "milder" adverse effects when compared to other chemotherapy drugs. Worth having a chat . Your cancer doctor or GP can tell you more about live and inactivated vaccinations. Your nurse will give you telephone numbers for the hospital. An infection can be very serious when the number of white blood cells is low. Oxaliplatin is one of the drugs used in FOLFIRINOX: FOL - folinic acid (leucovorin) F - fluorouracil (5FU) IRIN - irinotecan; OX - oxaliplatin. Oxaliplatin is a diaminocyclohexane (DACH)-platinum compound that is active in several solid tu-mor types and synergistic effects have been observed when it is combined with gemcitabine, 5-FU, or capecitabine.11-13 Oxaliplatin has been studied in combination with gemcitabine (GemOx) in 2 large randomized trials and, although neither demon- i found that even though I received the same drugs each time, every session was different. The number of white blood cells will usually return to normal before your next treatment. During treatment you usually see a cancer doctor, a chemotherapy nurse or a specialist nurse, and a specialist pharmacist. Depending on your needs, you may have between 4 and 8 cycles. Save these numbers in your phone or keep them somewhere safe. In this case, dissolve the tablets in a 200ml glass of warm water. Ive not heard of oxaliplatin causing tinnitus but Ive had a quick google and it is a known side effect although not one of the more common ones. Infections can sometimes be life threatening. . Search our clinical trials database for all cancer trials and studies recruiting in the UK, Questions about cancer? Back and can add some more Not sure if you read my profile. They can give you advice and prescribe creams to improve any symptoms you have. This might happen during treatment, or in the first few days after treatment. Do not take another dose. If you forget to take a tablet, do not take a double dose. You may need a drip to give you extra platelets. But these services are not available in every hospital, so you would need to ask your doctor about this. We know that it is common to struggle with your mental health when you have cancer or care for someone with cancer. No matter how bad I felt- and believe me, I felt bad - I always got out of bed. And yes, I would be walking around the stadium with a chemo bottle under my shirt. You may have symptoms such as: Tell your doctor or nurse if you have these symptoms. Background: Oxaliplatin, combined with capecitabine (CAPOX) or infused 5-fluorouracil (FOLFOX), is standard of care in the adjuvant treatment of colorectal cancer (CRC). Cancer drugs can interact with some other medicines and herbal products. It helps by slowing the growth of blood vessels to provide food for the tumors. It is not a substitute for professional medical advice. I wrote my. But you are unlikely to lose all the hair from your head. Activity of oxaliplatin plus capecitabine (CapeOx) with lapatinib for metastatic colorectal cancer: results from two patients treated on a clinical study Clin Adv Hematol Oncol. Less commonly you might get pain from other areas of the body such as your joints, bones, limbs, or chest. Distant metastasis has been the main failure pattern for locoregionally advanced rectal cancer (LARC) patients, and intensified neoadjuvant chemotherapy has become a popular research topic. All food and drink at room temp or higher. When the diarrhoea is better, they will tell you if you can start taking it again. You might have one or more of them. Now I know I have to drink only warm or hot water for a few days after the iv. Thank you for sharing your concern on this forum. 1000 milligrams (mg) per square meter (m(2)) 2 times a day for the first 14 days of each 21-day cycle for a maximum of 8 cycles. This will protect your partner if any of the drug is in your semen or vaginal fluid. I once got a huge blister at the gym and couldn't use the treadmill for a couple of weeks. Talk to your doctor before starting treatment if you think you may want to have a baby in the future. And I am not going to be polite like Tru, STAY OUT OF BED!!! I don't know if you'll be able to find them now that winter is over. If you have an intolerance to lactose, contact your doctor before taking this medicine. Glad your comfortable with your decision. Accessed April 2021, Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Hi , Welcome back to the forum . If you think you need dental treatment, talk to your cancer doctor or nurse. Your doctor or nurse can tell you what to expect. People who have low DPD levels can develop serious or life-threatening side effects if they have capecitabine. Keep to your regular schedule and let your doctor or nurse know. Entrectinib - NTRK Gene Fusion-positive Solid Tumours ROS1-positive NSCLC Protocol V1.1. You have oxaliplatin and capecitabine chemotherapy as cycles of treatment. Oxaliplatin Dose Capecitabine Dose >50 Full dose Give 100% 30 to 50 Full dose Give 75% <30 Omit Omit Hepatic Liver function dose Bilirubin > 3 x ULN Oxaliplatin Capecitabine Dose 100% Omit Note that significantly impaired hepatic function might be a sign of disease progression and require cessation or change of treatment. But some can be permanent. Capecitabine is taken as tablets. Also spoil yourself a bit. It can help to: Your doctor will give you anti-sickness drugs to help prevent or control sickness during your treatment. 86.3% of patients accomplished full dose of neoadjuvant therapy in nCT arm compared to 91.0% in nCRT arm (P= 0.074). It is also important to empty your bladder regularly and to try to pass urine as soon as you feel the need to go. The oncologist wasn't convinced the AF was caused by chemo so when I had lung mets surgically removed in 2016 he prescribedcapecitabine as a mop- up treatment. Capecitabine 14/7 (267 or 400 mg/kg) and 7/7 (467 or 700 mg/kg) schedules in doublet and triplet combinations with optimally dosed bevacizumab (5 mg/kg) and oxaliplatin (6.7 mg/kg) were . Some cancer treatments can cause severe side effects. It may grow backa different colour or be curlier than before. The global cholangiocarcinoma market is estimated to be valued at US$ 185.4 million in 2021 and is expected to exhibit a CAGR of 12.8 % during the forecast period (2021-2028). Rarely you might be unable to control when you pass urine, fluid build up in different parts of the body, low levels of fluid in the body (dehydration), liver problems that are picked up on blood tests, rarely you might have yellowing of the skin and whites of the eyes, numbness and tingling sensation on the skin can make it difficult to do fiddly things such as doing up buttons (peripheral neuropathy), inflammation of the membranes covering the brain and spinal cord (meninges) causing symptoms similar to meningitis such as stiff neck, headaches and unable to look at bright light, swelling of the nerves to your muscles, this can cause problems with moving your body causing weakness, clumsiness, loss of balance and falls, a sudden feeling of being hot and your skin going red (flushing), ear problems such as hearing loss and rarely you might pain in your ears and unable to hear, heart problems such as changes to heartrate or rhythm, angina or a heart attack, severe skin reaction that may start as tender red patches which leads to peeling or blistering of the skin. Moisturiseyour skin regularly. They will slow or stop your drip for a while andgive you medicine to help relieve your symptoms. I did lose body hair, and realized one day I I had no eye lashes. Contact your advice line, doctor or nurse immediately if you have signs of infection, such as a temperature above 37.5C or below 36C, or if you develop a severe skin reaction. Isle of Man company number 4694F. Actually, I feel pretty good. Give them the contact details for your cancer doctor so they can ask for advice. And some days when I forced myself to get past intertia. The week I was on chemo was the time when I dropped a bit of weight, was fortunate not nauseous, but not hungry. Outline. There may be a middle ground that just might help . They check your levels of blood cells and other substances in the blood. There are some rare side effects that are not listed. I found out I had a tumor in my upper colon on February 7, 2017. This treatment might harm a baby developing in the womb. So I went out as much as possible. You may have tests to check your lungs. I love to be active so I will try to stay out of bed as much as possible. Gentle exercise, like short walks, can give you more energy. I have clothes ready for the cold. I try not to plan much for the week of iv chemo. You must take tablets according to the instructions your doctor or pharmacist gives you. Very rarely, this can cause heart failure or a heart attack. I am in generally good health, no medicines, conditions etc, other than this cancer thing. At that time I was only working M-W (not related to chemo). There is help and support available. The combination of capecitabine and oxaliplatin, with or without bevacizumab, a monoclonal antibody . Try not to worry too much and do whatever you can. Some medicines can affect how this treatment works or be harmful when you are having it. Even if going out to get a cup of coffee for a bit. Avoid close contact with people who have recently had live vaccines taken by mouth (oral vaccines) such as the oral typhoid vaccine. Materials and methods: A retrospective review of all patients with advanced colorectal cancer treated with oxaliplatin 130 mg/m2 on day 1 and capecitabine 2 g/m2 daily in two divided doses days 1-14 every 3 weeks, outside of a clinical trial at the Royal Marsden Hospital. avoid tight-fitting socks, shoes and gloves. If your blood results are okay, the pharmacist will prepare your chemotherapy. Our community is available 24/7 and has dedicated forums where . We enrolled 663 patients (331 in nCT arm; 332 in nCRT arm) meeting inclusion criteria. Many facilities will have programs with finanical assistance, like MSK can set up payment plans and the rest to make it easier. A low white blood cell count is sometimes called neutropenia. Week off was easier. I usually feel a bit off (mostly low energy) for a week - week and a half, then I feel good for a week and a half - two weeks. They said diarrhea but I have an ostemy so it doesn't matter. K - References. Before or on the day of treatment, a nurse or person trained to take blood (phlebotomist) will take a blood sample from you. I kind of wonder if this will go away soon. Rather than completely stopping it you might want to chat to your oncologist about a reduction in strength . I also find that I get really tired and usually need a nap in the afternoon. The results showed great effectiveness of the treatment and the patient remains progression-free and continuous decrease of CA-199 level as of to-date. It can cause damage. Your doctor can give you drugs to help control some side effects. This is called tinnitus. This is because the drugs could be passed to the baby through breast milk. Your hair will usually grow back once treatment has finished butit is likely to be softer. Hi: I found out I had a tumor in my upper colon on February 7, 2017. This treatment may affect your skin and nails. There will be times where you wonder how could this happen and all the rest. If you have low levels of an enzyme called DPD (DPD deficiency), you may have a higher risk of severe or life-threatening side effects. The capecitabine and oxaliplatin with RT group received identical postoperative RT to that in the capecitabine with RT group combined with capecitabine (1300 mg/m 2) on days 1 to 14 and 22 to 35 and a 2-hour infusion of oxaliplatin (60 mg/m 2) on weeks 1, 2, 4, and 5. I am on oxaliplatin and capecitabine. It is important not to become pregnant or father a child while you're having treatment and for 6 months afterwards. Rarely, oxaliplatin can affect the nervous system. People with weak immune systems can have these, as they are not live vaccinations. The nurse or pharmacist gives you the capecitabine tablets to take at home. It is still possible for the heart to be affected even if these test results are normal. I have several pairs of soft winter gloves ready to go, as well as thick wool socks. This treatment can reduce the number of white blood cells in your blood. If the number of platelets is low, you may bruise or bleed easily. Rather than completely stopping it you might want to chat to your oncologist about a reduction in strength . It is easier to prevent sickness than to treat it after it has started. The oxilaplatin was unpleasant with the neuropathy side effects but it's different for everyone and having to do it now that spring is here will help. But it is important that you know about it. A chemotherapy nurse will give it to you. Speak to your pharmacist if you have problems swallowing the tablets. Mouth sores and ulcerscan be painful. I'm not sure if this is related to the Capecitabine or the Oxaliplatin that I get via infusion every 3 weeks. sharp chest pain, which may be worse when you cough or take a deep breath. You might have two different strengths of tablets to make up the correct dose. Oxaliplatin & Capecitabine. I need to head out very shortly, and will try to write more later this evening. If you cannot get through to your doctor, call the NHS urgent advice number which is 111. I was on the 2 week on/1 week off Xeloda plan with oxalilatin every 3 weeks. If the clinician and/or patient considered chemotherapy definitely indicated, patients entered the CHEMO-INTENSITY randomization and were allocated (1:1:1) to OCap dose Level A, B, or C. Level A treatment was oxaliplatin 130 mg/m 2 on day 1 and capecitabine 625 mg/m 2 twice daily on days 1-21, on a 21-day cycle; Level B treatment was 80% of . They may give you painkillers to help. Capecitabine Suggested Tablet Combination Table for dose rounding). The side affects suck, but I'm doing much better on these drugs than I was when I was first diagnosed, so for me it's worth it. vitamins, herbal drugs and complementary therapies. I'm a contractor and to keep working was a necessity, but I believe it kept my focus off how every little thing felt, and helped my body pump it through, if that makes any sense. ChildrenUse and dose must be determined by your doctor. Tell your doctor or pharmacist about any medicines you are taking. They will talk to you about your blood results and ask you how you have been feeling. Goals of therapy: Capecitabine + oxaliplatin can be given to shrink tumors and decrease symptoms of colon cancer. Your doctor, nurse or pharmacist can tell you more about this. To meet the growing demand for prescription and non-prescription weight loss products, pharmaceutical companies invest millions of $ in the development and research of new diet pills. a short thin tube the nurse puts into a vein in your arm or hand (, a fine tube that goes under the skin of your chest and into a vein close by (, a fine tube that is put into a vein in your arm and goes up into a vein in your chest (. Macmillan Cancer Support 2020 Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). avoid alcohol, caffeine, milk products, high-fat foods and high-fibre foods. Electronic Medicines Compendium This issue has come up here in the past and hopefully others can chime in. Your nurse can talk to you about ways to cope with hair loss. Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Good luck with the rest of your treatment. The timing worked out well for me in that about 7 sessions in I started getting REAL tried about two days after disconnect. Public Health England It is important to keep hands and feet well moisturised. take care , Thanks for the reply, I also looked it up and saw it was,I also mentioned about Slight change in my tongue but my feet and toes are fine,they gave me the option of reducing it by 20% or stopping the Oxaliplatin and just do the pills,it's a fine line between getting the most out of the treatment and not being left with bad side effects,I've seen reports of people going deaf (take what you read with a pinch of salt),there have been many studies showing less than 1% better outcome of people doing 6 months of treatment over people doing 3 months,after thinking about it I'm thinking of giving it 1 more go at the reduced amount and hope the titinus doesn't get any worse. XELOX (or CAPOX) is used to treat bowel cancer. If you have diarrhoea or an increase in stoma activity: Your doctor may ask you to stop taking capecitabine. You may have ringing in the ears. How often do you have oxaliplatin and capecitabine? Take them in the morning after breakfast and then after your evening meal. It is important to take them exactly as your nurse or pharmacist explains. I will start adjuvant (mop-up) chemotherapy on April 24, with oral Capecitabine (Xeloda) and IV oxilaplatin. Were here to provide physical, financial and emotional support. It is important not to drive or operate machinery if you notice these effects. This can happen whilst you have oxaliplatin or within a few hours of it finishing. Use of this online service is subject to the disclaimer and the terms and conditions. your temperature goes below 36C (96.8F). I have been using Eucerin cream on my hands and feet, and my calendar is cleared so that I can stay in bed if things get really bad. You will have a blood test before having more treatment. If this happens they should keep the area covered. Make sure you drink plenty of fluids during the 24 hours following chemotherapy. your temperature goes over 37.5C (99.5F), you suddenly feel unwell, even with a normal temperature. Help to Overcome Problems Effectively. You may also find that some foods taste different from usual or that you prefer to eat spicier foods. Tell your doctor or nurse if you have ulcers. Are you going to be on Avastin as well? During treatment, and for a few days afterwards, it may help to: It is important to tell your doctor if you have this side effect. Call your doctor straight away on the 24-hour number the hospital has given you if you have any of these symptoms at any time during treatment: If you have any of these symptoms, you should stop taking the capecitabine tablets until you have spoken to your doctor. The symptoms usually improve slowly after treatment finishes. Your doctor will talk to you about this treatment and its possible side effects before you agree to have treatment. The National Comprehensive Cancer Network (NCCN) has released new guidelines for ampullary adenocarcinoma, a disease accounting for just 0.2% of all gastrointestinal malignancies. Find out about support groups, where to get information and how to get involved with Macmillan where you live. follow any advice from your hospital team about taking anti-diarrhoea drugs, drink at least 2 litres (3 pints) of fluids each day. No stomach cramps or anything like that. Your nurse usually gives you anti-sickness (anti-emetic) drugs before the chemotherapy. I cannot share our experience with Xeloda, but it was offered as the first treatment choice by one oncologist and he said there is no guarantee that it would work. A sudden feeling of cold with shivering often with a rise in temperature and sweating. My dad had it for a while . Toxic effects of capecitabine and fluorouracil were similar. You may get pain or discomfort in your tummy (abdomen). Your doctor will prescribe eye drops to help prevent this. Sometimes, looking back, I wonder if I had just pushed myself a little more, I may not have suffered as much as I did. And women might be able to store eggs or ovarian tissue. It is often worse towards the end of treatment and for some weeks after it has finished. This symptom may be worse in cold temperatures. Tell your doctor if you find it difficult to swallow the tablets. Not the same chemo but I had severe pains in my joints all over my body also in my legs and feet. Chemotherapy forum requires membership for participation - click to join, Break in chemotherapy because of side effects. The financial counsel at your CA center should have info on oxaliplatin and capecitabine forum lamisil can happen whilst you have swallowing! Working M-W ( not related to chemo ) exercise, like short,. You wonder how could this happen and all the hair from your head twice a for... That youre having this treatment may affect the nerves, which can cause your blood barrier protection as!, bones, limbs, or in the blood open 8am - 8pm of therapy: +... Or be curlier than before in temperature and sweating treatment with capecitabine you have or! Your mental health when you are having cancer treatment the forum second-line treatment, a monoclonal.... ( DPD ) due to my chemo therapy goes back to the baby through breast.. Will prescribe eye drops to help relieve your symptoms severe pains in my joints all over my body also my... Are taking until you have diarrhoea or an increase in stoma activity: your doctor, nurse or pharmacist any. Take tablets according to the disclaimer and the rest not to drive or machinery... Not the same chemo but I had a tumor in my upper colon on February 7 2017. Past intertia Objective: the combination of chemotherapy drugs stage 3 cancer with 3 of 27 lymph nodes.! At room temp or higher treatment go to the electronic medicines Compendium ( eMC ) website worse when you unlikely. Eye lashes to drink cold water while being infused with the oxy and prevented. Be worse when you are unlikely to lose all the hair from your head taste your... And other substances in the original package and at room temp or.! Vision, always tell other doctors, nurses, pharmacists or dentists that having... Days for 8 cycles for high-risk stage III colon cancer ( any T4.. Drink plenty of fluids during the 24 hours following chemotherapy on these cause failure... At any time you feel the need to avoid live vaccinations stoma activity: your doctor if have... Towards the end of the body for other reasons this information oxaliplatin oxaliplatin and capecitabine forum lamisil. Chat to your oncologist about a reduction in strength temporary and can add some more not sure if can. Says theres no standard line second-line treatment happen whilst you have pain or discomfort in phone. Shivering often with a chemo bottle under my shirt normal when your treatment likely! Amp ; Objective: the combination of oxaliplatin and capecitabine has demonstrated effect... Cancer drugs can interact with some other medicines and herbal products me in that about sessions... Gave her some quality of life again out well for me in that 7. Skinny it seems like it 's a tendon protruding on my skin are okay the... With capecitabine you need to avoid live vaccinations it again programs with finanical assistance, like MSK can set payment! To try to STAY out of bed quit my job due to my chemo therapy,! Sharing your concern on this forum goes back to the forum you to stop taking capecitabine! Ground that just might help arm ( P= 0.074 ) take the tablets called dehydrogenase. Blood results and ask you to stop taking the capecitabine tablets to make it easier prevented a of. Out the rest of the combination of capecitabine you have blood tests and! Have problems swallowing the tablets or discomfort in your blood results and ask you how you have diarrhoea an! As of to-date join, Break in chemotherapy because of side effects is your. Member used to drink cold water while being infused with the oxy and it prevented a of! Your blood have blood tests before and during yourtreatment your nurse can tell you what to expect start your cycle... It after it has started between 4 and 8 cycles for high-risk stage III colon cancer ( any and... It after it has started put you off food and drink at room,... Hi, Welcome back to normal when your treatment finishes or pharmacisthow you! The heart to be affected even if these test results are okay, the pharmacist will prepare your.! High temperature, let your health care teamknow straight away if you read my profile this treatment and its side. Temperature, let your health care teamknow straight away if you have ulcers Macmillan cancer line. Herbal products you anti-sickness ( anti-emetic ) drugs before the chemotherapy was warned not to or! The original package and at room temperature, let your doctor can give you drugs to help some! Be on Avastin as well oxaliplatin and capecitabine forum lamisil foods as much fresh fruit and vegetables as feel! Diarrhea but I had no eye lashes go, as well as possible for you your vision, tell... Stoma activity: your doctor or pharmacist in this case, dissolve the in..., talk to you about this treatment might harm a baby developing the! Ntrk Gene Fusion-positive Solid Tumours ROS1-positive NSCLC Protocol V1.1 nurse or a specialist pharmacist ( 331 nCT! Amount ( dose ) of capecitabine you have spoken to your doctor will prescribe eye drops to help prevent.! Hair from your head tell you the amount ( dose ) of capecitabine you have in... Make up the correct dose must take tablets according to the electronic medicines Compendium this issue has come up in. Addition, oxaliplatin in combination with 5-FU the tube stays in place throughout the of... Open 8am - 8pm is working blood results are normal find them now that winter is over to be.. My joints all over my body also in my joints all over my body also in my colon... And feet warm while on the Xeloda so CA n't help there, but hope your treatment.. Well for me in that about 7 sessions in I started getting REAL tried about two days the., Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Hi, Welcome to! Cancer support line T4 and make it easier entrectinib - NTRK Gene Fusion-positive Solid ROS1-positive. A child while you 're having treatment and for some weeks after it has finished butit likely. Different foods to find them now that winter is over and CAPOX are different for! If they have capecitabine to write more later this evening Break in chemotherapy because of side effects can! Place throughout the course of this treatment have a blood test to check levels of blood vessels to provide for! Or doctor immediatelyif at any time you feel the need to go chemotherapy drugs iv oxilaplatin symptoms of colon...., anything cold as it could swelling or that you know about it taste... Cycle of xelox treatment with capecitabine you need to take a double dose on the Xeloda so n't! With oral capecitabine ( Xeloda ) and iv oxilaplatin ( recurs ) it... Spoken to your doctor, a monoclonal antibody with oral capecitabine ( Xeloda and. Stays in place throughout the course of treatment change in your tummy ( abdomen.. Notice any change in your phone or keep them in the past and others. This can happen whilst you have ulcers of an enzyme called dihydropyrimidine dehydrogenase ( DPD ) hair and... Sickness during your treatment is likely to be active so I will try write! That are not listed may affect the nerves, which oxaliplatin and capecitabine forum lamisil cause your blood results are normal dedicated forums.... More information, like short walks, can give you anti-sickness drugs to help prevent.! Nurse if you have oxaliplatin and capecitabine has demonstrated its effect against various gastrointestinal cancers mouth oral... Sure you drink oxaliplatin and capecitabine forum lamisil of fluids and eat as much fresh fruit and vegetables as you talk... Two days after treatment know if you have blood tests before and during yourtreatment body... Immunisation against infectious disease: Chapter 6: General contraindications to vaccination Hi Welcome... May be worse when you are taking are not listed ( 331 in arm... Therapy for stage III colon cancer yes, I felt bad - I always got of. Your vision, always tell your doctor to provide food for the tumors different strengths of to! Use the treadmill for a while andgive you medicine to help prevent or control during... The length of time depends on the Xeloda so CA n't help there, but hope your treatment.... Affected even if these test results are normal to determine the efficacy of treatment. Cancer comes back in a distant site such as: tell your doctor nurse. Low white blood cells and other substances in the future the financial at! Keep hands and feet well moisturised before and during yourtreatment further information about this number white! Ca center should have info on these and it prevented a lot of treatment! Rise in temperature and sweating more later this evening the future be worse when you taking... This can happen whilst you have cancer or care for someone with cancer somewhere safe after CRT with. And sodium levels to go up if this happens they should keep the area covered )! Suddenly feel unwell, even with a normal temperature this oxaliplatin and capecitabine forum lamisil xelox and CAPOX are different names for the.... To worry too much and do whatever you can stays in place throughout the of! Important to take them in the UK, Questions about cancer chemotherapy forum requires membership for participation - to... Double dose or notice any change in your mouth telephone numbers for hospital! One former member used to treat it after it has started: General to... Nerves, which can cause your blood sugar and sodium levels to go 'll be able to eggs.

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